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Order NO. D623573

人WRAP53抗原（重組蛋白）

英文名	Human WRAP53 Antigen (Recombinant Protein)
別名	DKCB3; TCAB1; WDR79
相關類別	抗原	儲存	冷凍（-20℃）
在線谘詢

編號	規格	庫存	目錄價（￥）	您的價格（￥）	數量
D623573-0001	1 MG	預計30日內發貨	待詢價	待詢價	－ +
D623573-0050	50 UG	預計30日內發貨	待詢價	待詢價	－ +
D623573-0100	100 UG	預計30日內發貨	待詢價	待詢價	－ +

產品描述

概述

Fusion protein corresponding to a region derived from 349-548 amino acids of human WRAP53

屬性

Full name:	WD repeat containing antisense to TP53
Synonyms:	DKCB3; TCAB1; WDR79
Swissprot:	Q9BUR4
Gene Accession:	BC002336
Gene ID:	55135
Purity:	>85%, as determined by Coomassie blue stained SDS-PAGE
Expression system:	Escherichia coli
Tags:	His tag C-Terminus, GST tag N-Terminus
Research areas:	Cell Biology
Reconstitution:	Reconstitute with sterile distilled water or deionized water to 1 mg/ml
Background:	This gene encodes an essential component of the telomerase holoenzyme complex, a ribonucleoprotein complex required for telomere synthesis. This protein is enriched in Cajal bodies, nuclear sites of RNP processing that are important for telomerase function. It interacts with dyskerin, TERT and TERC, other components of active telomerase, and with small Cajal body RNAs (scaRNAs), which are involved in modifying splicing RNAs. This mRNA also functions as a p53 antisense transcript, that regulates endogenous p53 mRNA levels and further induction of p53 protein by targeting the 5' untranslated region of p53 mRNA. Alternatively spliced transcript variants which differ only in the 5' UTR have been found for this gene. [provided by RefSeq, Mar 2011] (The background information is obtained from official databases and does not represent the product information.)

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