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Order NO. D225873
兔抗IFT57多克隆抗體
| 編 號 | 包裝 | 庫存 | 目錄價（￥） | 您的價格（￥） | 數 量 |
| D225873-0025 | 25 ul | 現貨 |
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| D225873-0100 | 100 ul | 現貨 |
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| D225873-0200 | 200 ul | 現貨 |
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產品描述
概述
Required for the formation of cilia. Plays an indirect role in sonic hedgehog signaling, cilia being required for all activity of the hedgehog pathway (By similarity). Has pro-apoptotic function via its interaction with HIP1, leading to recruit caspase-8 (CASP8) and trigger apoptosis. Has the ability to bind DNA sequence motif 5'-AAAGACATG-3' present in the promoter of caspase genes such as CASP1, CASP8 and CASP10, suggesting that it may act as a transcription regulator; however the relevance of such function remains unclear.
應用
酶聯免疫吸附測定（ELISA），免疫組織化學（IHC）
屬性
| 保存緩衝液 | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| 運輸條件 | 2-8°C |
| 靶點 Uniprot 登記號 | Q9NWB7 |
| 靶點基因 ID | 55081 |
| 靶點全稱 | intraflagellar transport 57 |
| 靶點別名 | HIPPI; MHS4R2; ESRRBL1 |
| 靶點研究領域 | Neuroscience |
| 亞型 | Immunogen-specific rabbit IgG |
相關文檔
Sample Application
