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Order NO. D224166
兔抗UNC13B多克隆抗體
英文名 Anti-UNC13B rabbit polyclonal antibody
別名 UNC13; MUNC13; Unc13h2
相關類別 一抗 儲存 冷凍(-20℃)
宿主 Rabbit 反應種屬 Human, Mouse, Rat
克隆類型 rabbit polyclonal 抗原 UNC13B
   
編 號 包裝 庫存 目錄價(¥) 您的價格(¥) 數 量
D224166-0025 25 ul 現貨
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D224166-0100 100 ul 現貨
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D224166-0200 200 ul 現貨
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產品描述

概述

This gene is expressed in the kidney cortical epithelial cells and is upregulated by hyperglycemia. The encoded protein shares a high level of similarity to the rat homolog, and contains 3 C2 domains and a diacylglycerol-binding C1 domain. Hyperglycemia increases the levels of diacylglycerol, which has been shown to induce apoptosis in cells transfected with this gene and thus contribute to the renal cell complications of hyperglycemia. Studies in other species also indicate a role for this protein in the priming step of synaptic vesicle exocytosis.

應用

酶聯免疫吸附測定(ELISA),免疫組織化學(IHC)

屬性

保存緩衝液 -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
運輸條件 2-8°C
靶點 Uniprot 登記號 O14795
靶點基因 ID 10497
靶點全稱 unc-13 homolog B
靶點別名 UNC13; MUNC13; Unc13h2; munc13-2
靶點研究領域 Signal Transduction, Neuroscience
亞型 Immunogen-specific rabbit IgG
相關文檔
Sample Application

  • The image on the left is immunohistochemistry of paraffin-embedded Human colorectal cancer tissue using D224166(UNC13B Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: ×200)

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