Order NO. D224165
產品描述
概述
This gene encodes a uridine 5'-monophosphate synthase. The encoded protein is a bifunctional enzyme that catalyzes the final two steps of the de novo pyrimidine biosynthetic pathway. The first reaction is carried out by the N-terminal enzyme orotate phosphoribosyltransferase which converts orotic acid to orotidine-5'-monophosphate. The terminal reaction is carried out by the C-terminal enzyme OMP decarboxylase which converts orotidine-5'-monophosphate to uridine monophosphate. Defects in this gene are the cause of hereditary orotic aciduria. Alternate splicing results in multiple transcript variants.
應用
酶聯免疫吸附測定(ELISA),免疫組織化學(IHC)
屬性
保存緩衝液 |
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
|
運輸條件 |
2-8°C
|
靶點 Uniprot 登記號 |
P11172
|
靶點基因 ID |
7372
|
靶點全稱 |
uridine monophosphate synthetase
|
靶點別名 |
OPRT
|
靶點研究領域 |
Epigenetics and Nuclear Signaling, Metabolism
|
亞型 |
Immunogen-specific rabbit IgG
|