Order NO. D222915
產品描述
概述
This gene encodes an antigen that is preferentially expressed in human melanomas and that is recognized by cytolytic T lymphocytes. It is not expressed in normal tissues, except testis. The encoded protein acts as a repressor of retinoic acid receptor, and likely confers a growth advantage to cancer cells via this function. Alternative splicing results in multiple transcript variants.
應用
酶聯免疫吸附測定(ELISA),免疫組織化學(IHC)
屬性
保存緩衝液 |
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
|
運輸條件 |
2-8°C
|
靶點 Uniprot 登記號 |
P78395
|
靶點基因 ID |
23532
|
靶點全稱 |
PRAME nuclear receptor transcriptional regulator
|
靶點別名 |
MAPE; OIP4; CT130; OIP-4
|
靶點研究領域 |
Epigenetics and Nuclear Signaling, Cancer
|
亞型 |
Immunogen-specific rabbit IgG
|