Order NO. D194830
產品描述
概述
The protein encoded by this gene is highly similar to the gene product of Schizosaccharomyces pombe rad21, a gene involved in the repair of DNA double-strand breaks, as well as in chromatid cohesion during mitosis. This protein is a nuclear phospho-protein, which becomes hyperphosphorylated in cell cycle M phase. The highly regulated association of this protein with mitotic chromatin specifically at the centromere region suggests its role in sister chromatid cohesion in mitotic cells.
應用
免疫印跡(WB),免疫熒光(IF),流式細胞術(FCM)
屬性
保存緩衝液 |
-20°C, PBS (PH 7.4) containing 0.05% sodium azide.
|
運輸條件 |
2-8°C
|
靶點 Uniprot 登記號 |
O60216
|
靶點基因 ID |
5885
|
靶點全稱 |
RAD21 cohesin complex component
|
靶點別名 |
MGS; HR21; MCD1; NXP1; SCC1; CDLS4; hHR21; HRAD21
|
靶點研究領域 |
Cancer, Epigenetics and Nuclear Signaling
|
亞型 |
IgG1
|