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編 號 | 包裝 | 庫存 | 目錄價(¥) | 您的價格(¥) | 數 量 |
D125873-0025 | 25 ul | 現貨 |
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D125873-0100 | 100 ul | 現貨 |
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D125873-0200 | 200 ul | 現貨 |
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概述
Required for the formation of cilia. Plays an indirect role in sonic hedgehog signaling, cilia being required for all activity of the hedgehog pathway (By similarity). Has pro-apoptotic function via its interaction with HIP1, leading to recruit caspase-8 (CASP8) and trigger apoptosis. Has the ability to bind DNA sequence motif 5'-AAAGACATG-3' present in the promoter of caspase genes such as CASP1, CASP8 and CASP10, suggesting that it may act as a transcription regulator; however the relevance of such function remains unclear.
應用
酶聯免疫吸附測定(ELISA),免疫組織化學(IHC)
屬性
保存緩衝液 | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
運輸條件 | 2-8°C |
靶點 Uniprot 登記號 | Q9NWB7 |
靶點基因 ID | 55081 |
靶點全稱 | intraflagellar transport 57 |
靶點別名 | HIPPI; MHS4R2; ESRRBL1 |
靶點研究領域 | Neuroscience |
亞型 | Immunogen-specific rabbit IgG |