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| 編 號 | 規格 | 庫存 | 目錄價（￥） | 您的價格（￥） | 數 量 |
| C600418-0010 | 10 UG | 谘詢 | 待詢價 | 待詢價 |
概述
Bcl-xL is a transmembrane protein located in the mitochondrial membranes of cells that are long-lived and postmitotic, such as adult brain cells. It plays a role in the signal transduction pathway of the FAS-Ligand. Bcl-xL is an anti-apoptotic protein which is a member of the Bcl-2 family which are able to form heterodimers, and this is an significant event in the regulation of apoptosis. It is involved in the survival of cancer cells. Bcl-xL is the leading monitor of apoptosis/active cell suicide. It has cell death repressor activity and therefore acts as a survival protein. The human Bcl-xL shares 97 % a.a. sequence identity with murine and rat Bcl-xL.
使用說明
This material is offered by Sangon Biotech for research, laboratory or further evaluation purposes. NOT FOR HUMAN USE.
屬性
| Physical Appearance | Sterile Filtered White lyophilized (freeze-dried) powder. |
| Purity | > 97 % by SDS-PAGE and HPLC analyses. |
| Source | Escherichia coli. |
| Biological Activity | Test in Process. |
| Formulation | Lyophilized from a 0.2 μm filtered concentrated solution in 20 mM Tris-HCl, pH 8.0, 5 % Trehalose. |
| Endotoxin | Less than 0.1 EU/μg of rHuBcl-xL as determined by LAL method. |
| Reconstitution | We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1 % BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at ≤ -20 °C. Further dilutions should be made in appropriate buffered solutions. |
| AA Sequence | SQSNRELVVD FLSYKLSQKG YSWSQFSDVE ENRTEAPEGT ESEMETPSAI NGNPSWHLAD SPAVNGATGH SSSLDAREVI PMAAVKQALR EAGDEFELRY RRAFSDLTSQ LHITPGTAYQ SFEQVVNELF RDGVNWGRIV AFFSFGGALC VESVDKEMQV LVSRIAAWMA TYLNDHLEPW IQENGGWDTF VELYGNNAAA ESRKGQERFN R |
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