Order NO. D261586
兔抗CDK12多克隆抗體
| 英文名 | Anti-CDK12 rabbit polyclonal antibody | ||
| 別名 | cyclin dependent kinase 12; CRK7; CRKR; CRKRS | ||
| 相關類別 | 一抗 | 儲存 | 冷凍（-20℃） |
| 宿主 | Rabbit | 反應種屬 | Human, Mouse, Rat |
| 標記物 | Unconjugate | 克隆類型 | rabbit polyclonal |
| 抗原 | CDK12 | ||
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| 編 號 | 包裝 | 庫存 | 目錄價（￥） | 您的價格（￥） | 數 量 |
| D261586-0025 | 25 ul | 現貨 |  |
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| D261586-0100 | 100 ul | 現貨 | |
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| D261586-0200 | 200 ul | 現貨 | |
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技術規格
| Background: | Cyclin-dependent kinase that phosphorylates the C-terminal domain (CTD) of the large subunit of RNA polymerase II (POLR2A), thereby acting as a key regulator of transcription elongation. Regulates the expression of genes involved in DNA repair and is required for the maintenance of genomic stability. Preferentially phosphorylates 'Ser-5' in CTD repeats that are already phosphorylated at 'Ser-7', but can also phosphorylate 'Ser-2'. Required for RNA splicing, possibly by phosphorylating SRSF1/SF2. Involved in regulation of MAP kinase activity, possibly leading to affect the response to estrogen inhibitors. |
| Applications: | ELISA, IHC |
| Name of antibody: | CDK12 |
| Immunogen: | Synthetic peptide of human CDK12 |
| Full name: | cyclin dependent kinase 12 |
| Synonyms: | CRK7; CRKR; CRKRS |
| SwissProt: | Q9NYV4 |
| ELISA Recommended dilution: | 5000-10000 |
| IHC positive control: | Human gastric cancer |
| IHC Recommend dilution: | 50-200 |
相關文檔
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Sample Application
