This gene encodes one of six different actin proteins. Actins are highly conserved proteins that are involved in cell motility, structure, integrity, and intercellular signaling. The encoded protein is a major constituent of the contractile apparatus and one of the two nonmuscle cytoskeletal actins that are ubiquitously expressed. Mutations in this gene cause Baraitser-Winter syndrome 1, which is characterized by intellectual disability with a distinctive facial appearance in human patients. Numerous pseudogenes of this gene have been identified throughout the human genome.
Applications:
WB
Name of antibody:
ACTB(HRP-Conjugate)
Immunogen:
Fusion protein of human ACTB
Full name:
actin beta
Synonyms:
BRWS1; PS1TP5BP1
SwissProt:
P60709
WB Predicted band size:
42 kDa
WB Positive control:
COS7, CHO-K1, C6, 3T3 and Hela cell lysates
WB Recommended dilution:
1000-5000
相關文檔
Sample Application
Gel: 8%SDS-PAGE, Lysate: 30 μg, Lane 1-5: COS7, CHO-K1, C6, 3T3 and Hela cell lysates, Primary antibody: D190826(ACTB(HRP-Conjugate) Antibody) at dilution 1/1000, Exposure time: 5 minutes