英文名 | DSP | ||
別名 | Dithiobis(succinimidylpropionate) | ||
相關類別 | 蛋白同源雙功能交鏈試劑 | 儲存 | 冷凍(-20℃) |
分子量 | 404.4 | ||
編 號 | 包裝 | 庫存 | 目錄價(¥) | 您的價格(¥) | 數 量 |
C110213-0100 | 100 MG | 現貨 |
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C110213-0500 | 500 MG | 現貨 |
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概述
DSP is a water-insoluble, homobifunctional N-hydroxysuccimide ester (NHS-ester) and DTSSP is its water-soluble analog. These crosslinkers are thiol-cleavable, primary amine-reactive and have been used in many applications. NHS-ester reactions with primary amines form covalent amide bonds that results in the release of N-hydroxysuccinimide. DSP is non-sulfonated and, therefore, is non-water-soluble whereas DTSSP is sulfonated and water-soluble.
應用
DSP is first dissolved in an organic solvent and added to the aqueous reaction mixture. Because DSP does not possess a charged group, it is lipophilic and membrane-permeable and is useful for intracellular and intramembrane conjugation.
組份
100 mg/bottle or 500 mg/bottle
技術規格
Molecular Weight | 404.42 |
Spacer arm | 12 |
Purity | >95% on TLC |
Formula | C14H16O8N2S2 |
Reactive group | NHS ester - homobifunctional cleavable |