概述

Traut’s Reagent (2-Iminothiolane or 2-IT) is a cyclic thioimidate compound for thiolation (sulfhydryl addition).Traut’sReagent reacts with primary amines (-NH2) to introduce sulfhydryl (-SH) groups while maintaining charge properties similar to the original amino group (Figure 1). Once added, sulfhydryl groups may be specifically targeted for reaction in a variety of useful labeling, cross-linking, and immobilization procedures.

應用

Soluble in water or buffer

組份

100 mg/bottle

技術規格

Molecular Weight	137.63
Purity	>98% on TLC
Absorption Maximum (in acetonitrile or 0.1 N HCl)	248 nm
Extinction Coefficient (in 0.1 N HCl)	8840 M-1 cm-1 (+/-5%)