英文名 | DSS | ||
別名 | Disuccinimidyl suberate | ||
相關類別 | 蛋白同源雙功能交鏈試劑 | 儲存 | 冷藏(2-8℃) |
分子量 | 368.4 | 無 | 辛二酸二琥珀酰亞胺 |
編 號 | 包裝 | 庫存 | 目錄價(¥) | 您的價格(¥) | 數 量 |
C100015-0100 | 100 MG | 現貨 |
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C100015-0500 | 500 MG | 現貨 |
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概述
DSS is a water-insoluble, homobifunctional N-hydroxysuccinimide ester (NHS ester),NHS esters react efficiently with primary amino groups (-NH2) in pH7-9 buffers to form stable amide bonds. The reaction results in the release of N-hydroxysuccinimide. Proteins, including antibodies, generally have several primary amines in the side chain of lysine (K) residues and the N-terminus of each polypeptide that are available as targets for NHS-ester reagents.
應用
DSS is hydrophobic and dissolved in an organic solvent such as DMSO or DMF then added to the aqueous reaction mixture. DSS does not possess a charged group and is lipophilic and membrane-permeable, which makes it useful for intracellular and intramembrane conjugations. Water-soluble BS3 possess a charged group and is useful for cell-surface protein crosslinking.
組份
100 mg/bottle or 500 mg/bottle
技術規格
Molecular Weight | 368.35 |
Spacer arm | 11.4 |
Purity | >95% on TLC |
Formula | C16H20N2O8 |